Takeshi Ishikawa Selected Research

Neoplasm Metastasis (Metastasis)

1/2021	Predictors for development of denosumab-induced hypocalcaemia in cancer patients with bone metastases determined by ordered logistic regression analysis.
1/2020	Metformin inhibits TGF‑β1‑induced epithelial‑mesenchymal transition and liver metastasis of pancreatic cancer cells.
6/2019	[Long-Term Survival of a Patient with Small Cell Esophageal Carcinoma Who Underwent Multidisciplinary Therapy-ACase Report].
7/2014	The inhibitory effect of heat treatment against epithelial-mesenchymal transition (EMT) in human pancreatic adenocarcinoma cell lines.
3/2009	Antitumor effect of pretreatment for colon cancer cells with hyperthermia plus geranylgeranylacetone in experimental metastasis models and a subcutaneous tumor model of colon cancer in mice.
11/2005	The radical scavenger edaravone enhances the anti-tumor effects of CPT-11 in murine colon cancer by increasing apoptosis via inhibition of NF-kappaB.
7/2004	Anoxia/reoxygenation down-regulates the expression of E-cadherin in human colon cancer cell lines.
1/2003	Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice.

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Takeshi Ishikawa Research Topics

Disease

53	Neoplasms (Cancer) 03/2024 - 01/2003
19	Colitis 10/2023 - 02/2002
19	Inflammation (Inflammations) 05/2023 - 01/2002
15	Stomach Neoplasms (Stomach Cancer) 12/2023 - 01/2002
13	Esophageal Neoplasms (Esophageal Cancer) 06/2022 - 08/2016
13	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 07/2020 - 02/2002
8	Ulcerative Colitis 10/2023 - 01/2012
8	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2003
8	Infections 10/2020 - 01/2006
7	Colorectal Neoplasms (Colorectal Cancer) 10/2023 - 02/2011
7	Esophageal Squamous Cell Carcinoma 11/2022 - 01/2016
7	Hyperthermia 07/2014 - 11/2003
6	Pancreatic Neoplasms (Pancreatic Cancer) 01/2020 - 05/2009
5	Ulcer 01/2021 - 04/2008
5	Prion Diseases (Transmissible Spongiform Encephalopathies) 10/2020 - 12/2009
5	Colonic Neoplasms (Colon Cancer) 03/2009 - 01/2003
4	Peripheral Nervous System Diseases (PNS Diseases) 07/2022 - 01/2013
4	Neutropenia 06/2022 - 12/2018
4	Hemorrhage 02/2022 - 01/2013
4	Wounds and Injuries (Trauma) 01/2022 - 06/2011
4	Adenocarcinoma 01/2022 - 02/2005
4	Carcinoma (Carcinomatosis) 08/2021 - 07/2004
4	Human Influenza (Influenza) 01/2020 - 01/2016
3	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2024 - 01/2022
3	Anemia 02/2023 - 03/2018
3	Autoimmune Diseases (Autoimmune Disease) 01/2023 - 02/2011
3	Breast Neoplasms (Breast Cancer) 07/2022 - 07/2019
3	Prostatic Neoplasms (Prostate Cancer) 06/2022 - 06/2020
3	Ischemia 03/2022 - 01/2003
3	Gastritis 01/2022 - 07/2010
3	Body Weight (Weight, Body) 01/2022 - 01/2005
3	Lung Neoplasms (Lung Cancer) 06/2020 - 01/2019
3	Carcinogenesis 03/2018 - 01/2002
3	Stomach Ulcer (Gastric Ulcer) 01/2018 - 04/2008
3	Arthritis (Polyarthritis) 12/2014 - 01/2005
2	Lymphatic Metastasis 01/2024 - 05/2019
2	Diarrhea 01/2024 - 01/2022
2	Cachexia 01/2023 - 05/2022
2	Disease Progression 11/2022 - 01/2019

Drug/Important Bio-Agent (IBA)

12	CytokinesIBA 06/2022 - 02/2002
11	Messenger RNA (mRNA)IBA 01/2022 - 07/2008
10	Proteins (Proteins, Gene)FDA Link 11/2022 - 07/2004
8	NF-kappa B (NF-kB)IBA 05/2009 - 02/2002
6	Therapeutic UsesIBA 01/2021 - 09/2013
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2011 - 05/2003
5	Biomarkers (Surrogate Marker)IBA 01/2024 - 06/2004
5	Fluorouracil (Carac)FDA LinkGeneric 06/2022 - 03/2017
5	Carbon MonoxideIBA 03/2022 - 01/2010
5	Dextran SulfateIBA 01/2022 - 02/2002
5	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2022 - 01/2013
5	Sulfonic AcidsIBA 01/2021 - 01/2011
4	C-Reactive ProteinIBA 10/2023 - 04/2003
4	NivolumabIBA 11/2022 - 08/2019
4	pembrolizumabIBA 11/2022 - 08/2019
4	AntigensIBA 11/2022 - 05/2015
4	Albumin-Bound Paclitaxel FDA Link 07/2022 - 02/2016
4	Docetaxel (Taxotere)FDA Link 06/2022 - 12/2008
4	Cisplatin (Platino)FDA LinkGeneric 06/2022 - 01/2017
4	pegfilgrastim (Neulasta)FDA Link 06/2022 - 03/2018
4	Heme Oxygenase-1IBA 03/2022 - 03/2013
4	Transcription Factors (Transcription Factor)IBA 01/2022 - 07/2003
4	Peroxidase (Myeloperoxidase)IBA 05/2021 - 03/2011
4	Prion ProteinsIBA 10/2020 - 12/2009
4	Irinotecan (Camptosar)FDA LinkGeneric 06/2019 - 11/2005
4	Gemcitabine FDA Link 01/2018 - 05/2009
4	DNA (Deoxyribonucleic Acid)IBA 01/2010 - 11/2003
3	Peptides (Polypeptides)IBA 10/2022 - 01/2018
3	Interleukin-8 (Interleukin 8)IBA 06/2022 - 01/2002
3	AntibodiesIBA 02/2022 - 12/2008
3	SolutionsIBA 01/2022 - 08/2012
3	Dextrans (Dextran)FDA Link 07/2020 - 05/2012
3	sodium sulfate (sodium bisulfate)FDA LinkGeneric 07/2020 - 05/2012
3	ZincIBA 11/2011 - 11/2002
3	polaprezinc (Z 103)IBA 11/2011 - 11/2002
3	Indomethacin (Indometacin)FDA LinkGeneric 06/2011 - 02/2011
2	Serum AlbuminIBA 01/2024 - 03/2021
2	Bevacizumab (Avastin)FDA Link 01/2024 - 01/2020
2	Angiogenesis InhibitorsIBA 01/2024 - 01/2020
2	afliberceptIBA 01/2024 - 01/2020
2	RamucirumabIBA 01/2024 - 01/2020
2	Volatile Fatty AcidsIBA 10/2023 - 05/2021
2	SteroidsIBA 10/2023 - 01/2012
2	Mesalamine (Mesalazine)FDA LinkGeneric 10/2023 - 11/2022
2	Hemoglobins (Hemoglobin)IBA 01/2023 - 05/2003
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2023 - 01/2022
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2023 - 11/2021
2	Interleukin-1 Receptor-Associated KinasesIBA 01/2023 - 01/2020
2	VaccinesIBA 11/2022 - 01/2019
2	130-nm albumin-bound paclitaxelIBA 07/2022 - 02/2016
2	Immune Checkpoint InhibitorsIBA 07/2022 - 10/2020

Therapy/Procedure

30	Therapeutics 03/2024 - 04/2003
24	Drug Therapy (Chemotherapy) 03/2024 - 12/2008
10	Lasers (Laser) 01/2022 - 03/2014
5	Enema (Enemas) 01/2021 - 01/2011
5	Immunotherapy 06/2020 - 07/2011
4	Radiotherapy 05/2019 - 02/2011
3	Chemoradiotherapy 06/2019 - 08/2016
2	Kampo Medicine (Kampo) 01/2024 - 01/2011
2	Esophagectomy 11/2022 - 12/2018
2	Cryotherapy (Therapy, Cold) 07/2022 - 02/2020